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autoStructN2V Training Process

Two-stage training with automatic structured noise detection and removal.

autoStructN2V training has three phases:

Stage 1: Initial N2V Training

Standard N2V training removes random noise. This produces an intermediate result where structured noise may still be visible.

Mask Extraction & Review

After Stage 1

  • The system analyzes residual noise patterns

  • A mask showing detected structure is generated

  • You can review and adjust the mask before proceeding

  • Options: Approve mask, regenerate with different settings, or skip Stage 2

Stage 2: Structure-Aware Training

A second model is trained using the noise mask. Masking follows the detected noise structure, teaching the network to specifically remove those patterns.

2.5D Mode Differences:

In 2.5D mode, the mask becomes 3-dimensional, capturing noise correlations across consecutive slices. The mask visualization shows three tabs (Z-1, Z center, Z+1) so you can inspect each slice's pattern before approving.

What to expect

  • Total training time is roughly 2x single-stage N2V

  • Stage 1 and Stage 2 can have different configurations

  • The mask review step requires your input before Stage 2 begins

  • Final results combine both stages for optimal noise removal

Part of DFG Priority Programme SPP2332 "Physics of Parasitism"